Cruz Azul have historically dominated this fixture, winning 13 of the previous 20 encounters. While the champions cruised to a 3-0 victory in their last meeting, the Alfonso Lastras has often been a site of competitive friction, with seven of the last nine matches between these two sides seeing both teams find the net.

• Cruz Azul are unbeaten in their last five competitive matches, including three wins in their final four games of the previous title-winning campaign.
• Atletico San Luis have kept three clean sheets in their last four matches across all competitions, including pre-season friendlies.
• The hosts are looking for their first league win since late April, when they defeated Atlas 1-0 away.
• Cruz Azul have scored at least two goals in four of their last five matches.

The visitors are missing Amaury Morales through injury, but the bigger concern is the potential absence of Jeremy Márquez; the midfielder is reportedly subject to summer transfer interest and may be rested to protect his valuation. San Luis boast a fully fit squad for Mejía’s debut, with new signing Sébastien Salles-Lamonge expected to pull the strings in midfield.

Cruz Azul will rely on the established trio of Agustín Palavecino, Carlos Rodriguez, and Carlos Rotondi to control the tempo, while San Luis look to Santiago Muñoz to lead the line after a promising pre-season.